What are the side effects of DHEA?

DHEA is a hormone. It might increase levels of androgen and have a steroid effect. The long-term safety of DHEA use hasn't been established. There are concerns that using DHEA as a supplement might increase the risk of hormone-sensitive cancers, including prostate, breast and ovarian cancers. The National Collegiate Athletic Association has banned DHEA use among athletes.

DHEA has been linked to:

• Reduced high-density lipoprotein (HDL), or "good," cholesterol levels
• Unwanted, male-pattern hair growth in women (hirsutism)
• Acne
• Mania and heart palpitations
• Oily skin

Supplements such as DHEA can also cause serious adverse effects when mixed with prescription or nonprescription drugs.